ctcRbase

Entry Detail

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General Information

Database ID: BRCA06041 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: STAU1 Full Name: staufen double-stranded RNA binding protein 1 Category: mRNA Synonyms: PPP1R150|STAU Chromosome: chr20 Strand: - Coordinate: Start Site(bp): 49113339 End Site(bp): 49188367 Gene Summary: Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000124214 HGNC ID: HGNC:11370 Entrez Gene: 6780

Expression Profile of STAU1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-138-5p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-142-3p YES YES YES hsa-miR-142-5p YES NO YES hsa-miR-143-3p YES YES NO hsa-miR-144-3p YES YES YES hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-187-3p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-223-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-301a-3p YES YES NO hsa-miR-301b-3p YES YES NO hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-326 YES YES NO hsa-miR-330-3p YES NO YES hsa-miR-330-5p YES YES NO hsa-miR-335-5p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-370-3p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-384 YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-454-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-876-5p YES YES NO Display: