ctcRbase

Entry Detail

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General Information

Database ID: BRCA06097 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: IRF6 Full Name: interferon regulatory factor 6 Category: mRNA Synonyms: LPS|OFC6|PIT|PPS|PPS1|VWS|VWS1 Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 209785623 End Site(bp): 209806175 Gene Summary: This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2011] External Links: Ensembl ID: ENSG00000117595 HGNC ID: HGNC:6121 Entrez Gene: 3664

Expression Profile of IRF6 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-138-5p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-320a YES YES YES hsa-miR-320b YES YES YES hsa-miR-320c YES YES YES hsa-miR-320d YES YES YES hsa-miR-340-5p YES YES NO hsa-miR-9-5p YES YES NO Display: