ctcRbase

Entry Detail

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General Information

Database ID: BRCA06211 Cancer Type: breast cancer Dataset: GSE75367 CTCs/CTM Isolation Method: micromanipulation immunofluorescence

Gene Information

ncRNA Symbol: DDX17 Full Name: DEAD-box helicase 17 Category: mRNA Synonyms: P72|RH70 Chromosome: chr22 Strand: - Coordinate: Start Site(bp): 38483440 End Site(bp): 38507660 Gene Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by DDX5 gene, are more closely related to each other than to any other member of the DEAD box family. This gene can encode multiple isoforms due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) start codon. [provided by RefSeq, Apr 2011] External Links: Ensembl ID: ENSG00000100201 HGNC ID: HGNC:2740 Entrez Gene: 10521

Expression Profile of DDX17 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1297 YES NO YES hsa-miR-130a-3p YES YES NO hsa-miR-130b-3p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-139-5p YES YES NO hsa-miR-1-3p YES YES YES hsa-miR-145-5p YES NO YES hsa-miR-186-5p YES YES NO hsa-miR-193a-3p YES YES NO hsa-miR-193b-3p YES YES NO hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-206 YES YES YES hsa-miR-212-3p YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-217 YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-222-3p YES YES NO hsa-miR-26a-5p YES NO YES hsa-miR-26b-5p YES NO YES hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-301a-3p YES YES NO hsa-miR-301b-3p YES YES NO hsa-miR-335-5p YES YES NO hsa-miR-338-3p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-34a-5p YES YES YES hsa-miR-34c-5p YES YES YES hsa-miR-361-5p YES YES NO hsa-miR-365a-3p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-421 YES YES YES hsa-miR-448 YES YES NO hsa-miR-449a YES YES YES hsa-miR-449b-5p YES YES YES hsa-miR-454-3p YES YES NO hsa-miR-490-3p YES YES YES hsa-miR-491-5p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-505-3p YES YES YES hsa-miR-520f-3p YES NO YES hsa-miR-542-3p YES YES NO hsa-miR-590-5p YES YES NO hsa-miR-613 YES YES YES hsa-miR-625-5p YES NO NO hsa-miR-642a-5p YES NO NO hsa-miR-875-5p YES YES YES hsa-miR-9-5p YES YES YES Display: