ctcRbase

Entry Detail

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General Information

Database ID: BRCA06216 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: HNRNPH3 Full Name: heterogeneous nuclear ribonucleoprotein H3 Category: mRNA Synonyms: 2H9|HNRPH3 Chromosome: chr10 Strand: + Coordinate: Start Site(bp): 68331174 End Site(bp): 68343191 Gene Summary: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes. Several alternatively spliced transcript variants have been noted for this gene, however, not all are fully characterized. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000096746 HGNC ID: HGNC:5043 Entrez Gene: 3189

Expression Profile of HNRNPH3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-139-5p YES YES NO hsa-miR-140-5p YES YES YES hsa-miR-142-5p YES NO YES hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-205-5p YES YES YES hsa-miR-221-3p YES YES YES hsa-miR-222-3p YES YES YES hsa-miR-224-5p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-29a-3p YES YES NO hsa-miR-29b-3p YES YES NO hsa-miR-29c-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-302a-3p YES YES NO hsa-miR-302b-3p YES YES NO hsa-miR-302c-3p YES YES NO hsa-miR-302d-3p YES YES NO hsa-miR-302e YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-369-3p YES NO NO hsa-miR-372-3p YES YES NO hsa-miR-373-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-411-5p YES YES YES hsa-miR-421 YES YES NO hsa-miR-429 YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-499a-5p YES YES NO hsa-miR-520a-3p YES YES NO hsa-miR-520b YES YES NO hsa-miR-520c-3p YES YES NO hsa-miR-520d-3p YES YES NO hsa-miR-520e YES YES NO hsa-miR-543 YES YES NO hsa-miR-599 YES YES NO hsa-miR-875-5p YES YES NO Display: