ctcRbase

Entry Detail

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General Information

Database ID: BRCA06282 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: GABRA1 Full Name: gamma-aminobutyric acid type A receptor alpha1 subunit Category: mRNA Synonyms: ECA4|EIEE19|EJM|EJM5 Chromosome: chr5 Strand: + Coordinate: Start Site(bp): 161847063 End Site(bp): 161899981 Gene Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000022355 HGNC ID: HGNC:4075 Entrez Gene: 2554

Expression Profile of GABRA1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-137 YES YES YES hsa-miR-139-5p YES YES YES hsa-miR-144-3p YES YES NO hsa-miR-155-5p YES YES YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-221-3p YES YES YES hsa-miR-222-3p YES YES YES hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-875-5p YES YES NO Display: