ctcRbase

Entry Detail

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General Information

Database ID: BRCA06398 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: IARS Full Name: isoleucyl-tRNA synthetase Category: mRNA Synonyms: GRIDHH|IARS1|ILERS|ILRS|IRS|PRO0785 Chromosome: chr9 Strand: - Coordinate: Start Site(bp): 92210207 End Site(bp): 92293756 Gene Summary: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found. [provided by RefSeq, Nov 2012] External Links: Ensembl ID: ENSG00000196305 HGNC ID: HGNC:5330 Entrez Gene: 3376

Expression Profile of IARS Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES YES hsa-miR-107 YES YES YES hsa-miR-1297 YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-153-3p YES YES YES hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-195-5p YES YES YES hsa-miR-217 YES YES YES hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-335-5p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-375 YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-497-5p YES YES YES hsa-miR-873-5p YES YES NO Display: