Entry Detail



General Information

Database ID:BRCA06489
Cancer Type:breast cancer
Dataset:GSE109761
CTCs/CTM Isolation Method:microfluidics immunofluorescence



Gene Information

ncRNA Symbol:GOT2
Full Name:glutamic-oxaloacetic transaminase 2
Category:mRNA
Synonyms:KAT4|KATIV|KYAT4|mitAAT
Chromosome:chr16
Strand:-
Coordinate:
Start Site(bp):58707131End Site(bp):58734357
Gene Summary:Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]
External Links:
Ensembl ID:ENSG00000125166
HGNC ID:HGNC:4433
Entrez Gene:2806



Expression Profile of GOT2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-128-3p
YES
YES
NO
hsa-miR-139-5p
YES
YES
YES
hsa-miR-143-3p
YES
YES
NO
hsa-miR-15a-5p
YES
YES
NO
hsa-miR-15b-5p
YES
YES
NO
hsa-miR-16-5p
YES
YES
NO
hsa-miR-181a-5p
YES
YES
YES
hsa-miR-181b-5p
YES
YES
YES
hsa-miR-181c-5p
YES
YES
YES
hsa-miR-181d-5p
YES
YES
YES
hsa-miR-194-5p
YES
YES
YES
hsa-miR-195-5p
YES
YES
NO
hsa-miR-197-3p
YES
YES
NO
hsa-miR-214-3p
YES
YES
NO
hsa-miR-216a-5p
YES
YES
NO
hsa-miR-216b-5p
YES
YES
NO
hsa-miR-217
YES
YES
NO
hsa-miR-27a-3p
YES
YES
NO
hsa-miR-27b-3p
YES
YES
NO
hsa-miR-30a-5p
YES
NO
YES
hsa-miR-30b-5p
YES
NO
YES
hsa-miR-30c-5p
YES
NO
YES
hsa-miR-30d-5p
YES
NO
YES
hsa-miR-30e-5p
YES
NO
YES
hsa-miR-320a
YES
NO
YES
hsa-miR-320b
YES
NO
YES
hsa-miR-320c
YES
NO
YES
hsa-miR-320d
YES
NO
YES
hsa-miR-424-5p
YES
YES
NO
hsa-miR-485-5p
YES
YES
NO
hsa-miR-494-3p
YES
YES
NO
hsa-miR-497-5p
YES
YES
NO
hsa-miR-543
YES
YES
NO
hsa-miR-874-3p
YES
YES
NO
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