ctcRbase

Entry Detail

---



General Information

Database ID: BRCA06495 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: ATP6V1E1 Full Name: ATPase H+ transporting V1 subunit E1 Category: mRNA Synonyms: ARCL2C|ATP6E|ATP6E2|ATP6V1E|P31|Vma4 Chromosome: chr22 Strand: - Coordinate: Start Site(bp): 17592136 End Site(bp): 17628818 Gene Summary: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain E subunit isoforms. Pseudogenes for this gene have been found in the genome. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000131100 HGNC ID: HGNC:857 Entrez Gene: 529

Expression Profile of ATP6V1E1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-429 YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-542-3p YES YES NO Display: