ctcRbase

Entry Detail

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General Information

Database ID: BRCA06519 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: TANK Full Name: TRAF family member associated NFKB activator Category: mRNA Synonyms: I-TRAF|ITRAF|TRAF2 Chromosome: chr2 Strand: + Coordinate: Start Site(bp): 161136908 End Site(bp): 161236221 Gene Summary: The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010] External Links: Ensembl ID: ENSG00000136560 HGNC ID: HGNC:11562 Entrez Gene: 10010

Expression Profile of TANK Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-128-3p YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-1297 YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-17-5p YES YES NO hsa-miR-190a-5p YES YES NO hsa-miR-190b YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-329-3p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-346 YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-378a-3p YES YES NO hsa-miR-384 YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-421 YES YES NO hsa-miR-422a YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-519d-3p YES YES NO hsa-miR-93-5p YES YES NO Display: