ctcRbase

Entry Detail

---



General Information

Database ID: BRCA06556 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: ACO2 Full Name: aconitase 2 Category: mRNA Synonyms: ACONM|HEL-S-284|ICRD|OCA8|OPA9 Chromosome: chr22 Strand: + Coordinate: Start Site(bp): 41469125 End Site(bp): 41528989 Gene Summary: The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000100412 HGNC ID: HGNC:118 Entrez Gene: 50

Expression Profile of ACO2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-127-3p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-184 YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-7-5p YES YES NO Display: