ctcRbase

Entry Detail

---



General Information

Database ID: BRCA06580 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: UBE2A Full Name: ubiquitin conjugating enzyme E2 A Category: mRNA Synonyms: HHR6A|MRXS30|MRXSN|RAD6A|UBC2 Chromosome: chrX Strand: + Coordinate: Start Site(bp): 119574467 End Site(bp): 119591083 Gene Summary: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] External Links: Ensembl ID: ENSG00000077721 HGNC ID: HGNC:12472 Entrez Gene: 7319

Expression Profile of UBE2A Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-129-5p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-144-3p YES YES YES hsa-miR-154-5p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-182-5p YES YES NO hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-212-3p YES YES NO hsa-miR-223-3p YES YES YES hsa-miR-31-5p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-376a-3p YES YES NO hsa-miR-376b-3p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-542-3p YES YES NO hsa-miR-876-5p YES YES NO Display: