Entry Detail



General Information

Database ID:BRCA06632
Cancer Type:breast cancer
Dataset:GSE41245
CTCs/CTM Isolation Method:CTC-Chip



Gene Information

ncRNA Symbol:SNF8
Full Name:SNF8, ESCRT-II complex subunit
Category:mRNA
Synonyms:Dot3|EAP30|VPS22
Chromosome:chr17
Strand:-
Coordinate:
Start Site(bp):48929316End Site(bp):48945117
Gene Summary:The protein encoded by this gene is a component of the endosomal sorting complex required for transport II (ESCRT-II), which regulates the movement of ubiquitinylated transmembrane proteins to the lysosome for degradation. This complex also interacts with the RNA polymerase II elongation factor (ELL) to overcome the repressive effects of ELL on RNA polymerase II activity. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
External Links:
Ensembl ID:ENSG00000159210
HGNC ID:HGNC:17028
Entrez Gene:11267



Expression Profile of SNF8 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-124-3p
YES
YES
YES
hsa-miR-129-5p
YES
YES
NO
hsa-miR-186-5p
YES
YES
NO
hsa-miR-340-5p
YES
YES
NO
hsa-miR-370-3p
YES
NO
YES
hsa-miR-506-3p
YES
YES
NO
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