ctcRbase

Entry Detail

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General Information

Database ID: BRCA06658 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: IPO7 Full Name: importin 7 Category: mRNA Synonyms: Imp7|RANBP7 Chromosome: chr11 Strand: + Coordinate: Start Site(bp): 9384622 End Site(bp): 9448126 Gene Summary: The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000205339 HGNC ID: HGNC:9852 Entrez Gene: 10527

Expression Profile of IPO7 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p NO YES YES hsa-miR-106b-5p NO YES YES hsa-miR-128-3p YES YES YES hsa-miR-129-5p NO YES YES hsa-miR-140-5p NO YES YES hsa-miR-142-3p NO YES YES hsa-miR-145-5p YES NO YES hsa-miR-153-3p NO YES YES hsa-miR-15a-5p NO YES YES hsa-miR-15b-5p NO YES YES hsa-miR-16-5p NO YES YES hsa-miR-17-5p NO YES YES hsa-miR-195-5p NO YES YES hsa-miR-205-5p YES NO YES hsa-miR-20a-5p NO YES YES hsa-miR-20b-5p NO YES YES hsa-miR-214-3p YES YES NO hsa-miR-22-3p YES YES YES hsa-miR-224-5p NO YES YES hsa-miR-300 NO YES YES hsa-miR-302a-3p NO YES YES hsa-miR-302b-3p NO YES YES hsa-miR-302c-3p NO YES YES hsa-miR-302d-3p NO YES YES hsa-miR-302e NO YES YES hsa-miR-320a YES NO YES hsa-miR-320b YES NO YES hsa-miR-320c YES NO YES hsa-miR-320d YES NO YES hsa-miR-372-3p NO YES YES hsa-miR-373-3p NO YES YES hsa-miR-381-3p NO YES YES hsa-miR-383-5p YES NO YES hsa-miR-424-5p NO YES YES hsa-miR-433-3p YES NO YES hsa-miR-448 NO YES YES hsa-miR-455-5p NO YES YES hsa-miR-489-3p YES NO YES hsa-miR-497-5p NO YES YES hsa-miR-503-5p NO YES YES hsa-miR-519d-3p NO YES YES hsa-miR-520a-3p NO YES YES hsa-miR-520b NO YES YES hsa-miR-520c-3p NO YES YES hsa-miR-520d-3p NO YES YES hsa-miR-520e NO YES YES hsa-miR-7-5p NO YES YES hsa-miR-93-5p NO YES YES Display: