ctcRbase

Entry Detail

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General Information

Database ID: BRCA06780 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: KRT80 Full Name: keratin 80 Category: mRNA Synonyms: KB20 Chromosome: chr12 Strand: - Coordinate: Start Site(bp): 52168996 End Site(bp): 52192000 Gene Summary: Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene's expression profile shows that it encodes a type II epithelial keratin, although structurally the encoded protein is more like a type II hair keratin. This protein is involved in cell differentiation, localizing near desmosomal plaques in earlier stages of differentiation but then dispersing throughout the cytoplasm in terminally differentiating cells. The type II keratins are clustered in a region of chromosome 12q13. Two transcript variants encoding two different fully functional isoforms have been found for this gene.[provided by RefSeq, Oct 2010] External Links: Ensembl ID: ENSG00000167767 HGNC ID: HGNC:27056 Entrez Gene: 144501

Expression Profile of KRT80 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-125a-5p YES YES NO hsa-miR-125b-5p YES YES NO hsa-miR-143-3p YES YES YES hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-216a-5p YES YES YES hsa-miR-216b-5p YES NO YES hsa-miR-29a-3p YES YES NO hsa-miR-29b-3p YES YES NO hsa-miR-29c-3p YES YES NO hsa-miR-31-5p YES YES NO hsa-miR-326 YES NO YES hsa-miR-330-5p YES NO YES hsa-miR-340-5p YES YES NO hsa-miR-370-3p YES YES NO hsa-miR-429 YES YES YES hsa-miR-7-5p YES YES NO hsa-miR-873-5p YES YES NO hsa-miR-874-3p YES YES NO hsa-miR-876-5p YES YES NO Display: