Entry Detail



General Information

Database ID:BRCA06785
Cancer Type:breast cancer
Dataset:GSE41245
CTCs/CTM Isolation Method:CTC-Chip



Gene Information

ncRNA Symbol:PPIE
Full Name:peptidylprolyl isomerase E
Category:mRNA
Synonyms:CYP-33|CYP33
Chromosome:chr1
Strand:+
Coordinate:
Start Site(bp):39692182End Site(bp):39763914
Gene Summary:The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities, and it also exhibits RNA-binding activity. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 1, has been identified. [provided by RefSeq, Aug 2010]
External Links:
Ensembl ID:ENSG00000084072
HGNC ID:HGNC:9258
Entrez Gene:10450



Expression Profile of PPIE Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-15a-5p
YES
YES
NO
hsa-miR-15b-5p
YES
YES
NO
hsa-miR-16-5p
YES
YES
NO
hsa-miR-195-5p
YES
YES
NO
hsa-miR-28-5p
YES
NO
YES
hsa-miR-296-3p
YES
YES
NO
hsa-miR-335-5p
YES
YES
NO
hsa-miR-424-5p
YES
YES
NO
hsa-miR-497-5p
YES
YES
NO
hsa-miR-708-5p
YES
NO
YES
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