ctcRbase

Entry Detail

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General Information

Database ID: BRCA06806 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: USP14 Full Name: ubiquitin specific peptidase 14 Category: mRNA Synonyms: TGT Chromosome: chr18 Strand: + Coordinate: Start Site(bp): 158383 End Site(bp): 214629 Gene Summary: This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000101557 HGNC ID: HGNC:12612 Entrez Gene: 9097

Expression Profile of USP14 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-124-3p YES YES YES hsa-miR-128-3p YES YES NO hsa-miR-143-3p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-195-5p YES YES YES hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-217 YES YES NO hsa-miR-219a-5p YES NO YES hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-320a YES NO YES hsa-miR-320b YES NO YES hsa-miR-320c YES NO YES hsa-miR-320d YES NO YES hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-488-3p YES YES YES hsa-miR-494-3p YES YES NO hsa-miR-497-5p YES YES YES hsa-miR-499a-5p YES YES NO hsa-miR-505-3p YES YES YES hsa-miR-506-3p YES YES YES hsa-miR-543 YES YES YES hsa-miR-9-5p YES YES YES Display: