ctcRbase

Entry Detail

---



General Information

Database ID: BRCA06816 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: GALNT6 Full Name: polypeptide N-acetylgalactosaminyltransferase 6 Category: mRNA Synonyms: GALNAC-T6|GalNAcT6 Chromosome: chr12 Strand: - Coordinate: Start Site(bp): 51351247 End Site(bp): 51392867 Gene Summary: This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. The encoded protein is capable of glycosylating fibronectin peptide in vitro and is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetal fibronectin. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000139629 HGNC ID: HGNC:4128 Entrez Gene: 11226

Expression Profile of GALNT6 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-132-3p YES YES NO hsa-miR-138-5p YES YES NO hsa-miR-140-5p YES YES NO hsa-miR-149-5p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-28-5p YES YES NO hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-328-3p YES YES NO hsa-miR-378a-3p YES YES NO hsa-miR-422a YES YES NO hsa-miR-708-5p YES YES NO Display: