ctcRbase

Entry Detail

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General Information

Database ID: BRCA06823 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: CCDC88C Full Name: coiled-coil domain containing 88C Category: mRNA Synonyms: DAPLE|HKRP2|HYC1|KIAA1509|SCA40 Chromosome: chr14 Strand: - Coordinate: Start Site(bp): 91271323 End Site(bp): 91417844 Gene Summary: This gene encodes a ubiquitously expressed coiled-coil domain-containing protein that interacts with the dishevelled protein and is a negative regulator of the Wnt signalling pathway. The protein encoded by this gene has a PDZ-domain binding motif in its C-terminus with which it interacts with the dishevelled protein. Dishevelled is a scaffold protein involved in the regulation of the Wnt signaling pathway. The Wnt signaling pathway plays an important role in embryonic development, tissue maintenance, and cancer progression. Mutations in this gene cause autosomal recessive, primary non-syndromic congenital hydrocephalus; a condition characterized by excessive accumulation of cerebrospinal fluid in the ventricles of the brain. [provided by RefSeq, Jan 2013] External Links: Ensembl ID: ENSG00000015133 HGNC ID: HGNC:19967 Entrez Gene: 440193

Expression Profile of CCDC88C Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES YES YES hsa-miR-128-3p YES YES YES hsa-miR-133a-3p YES YES NO hsa-miR-133b YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-142-3p YES YES NO hsa-miR-147a YES NO NO hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-199a-5p YES YES YES hsa-miR-199b-5p YES YES YES hsa-miR-218-5p YES YES NO hsa-miR-223-3p YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-543 YES YES YES hsa-miR-96-5p YES YES YES Display: