ctcRbase

Entry Detail

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General Information

Database ID: BRCA06836 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: SAE1 Full Name: SUMO1 activating enzyme subunit 1 Category: mRNA Synonyms: AOS1|HSPC140|SUA1|UBLE1A Chromosome: chr19 Strand: + Coordinate: Start Site(bp): 47113274 End Site(bp): 47210636 Gene Summary: Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010] External Links: Ensembl ID: ENSG00000142230 HGNC ID: HGNC:30660 Entrez Gene: 10055

Expression Profile of SAE1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-134-5p YES YES NO hsa-miR-138-5p YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-205-5p NO YES YES hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-371a-5p YES YES YES hsa-miR-382-5p NO YES YES hsa-miR-491-5p YES YES NO Display: