ctcRbase

Entry Detail

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General Information

Database ID: BRCA06893 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: MACC1 Full Name: MET transcriptional regulator MACC1 Category: mRNA Synonyms: 7A5|SH3BP4L Chromosome: chr7 Strand: - Coordinate: Start Site(bp): 20134655 End Site(bp): 20217404 Gene Summary: MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM, Mar 2009] External Links: Ensembl ID: ENSG00000183742 HGNC ID: HGNC:30215 Entrez Gene: 346389

Expression Profile of MACC1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-155-5p YES YES NO hsa-miR-329-3p YES NO NO hsa-miR-362-3p YES NO NO Display: