ctcRbase

Entry Detail

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General Information

Database ID: BRCA06933 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: HNRNPH2 Full Name: heterogeneous nuclear ribonucleoprotein H2 Category: mRNA Synonyms: FTP3|HNRPH'|HNRPH2|MRXSB|NRPH2|hnRNPH' Chromosome: chrX Strand: + Coordinate: Start Site(bp): 101408295 End Site(bp): 101414133 Gene Summary: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that binds to RNAs. It is very similar to the family member HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein. Read-through transcription between this locus and the ribosomal protein L36a gene has been observed. [provided by RefSeq, Jan 2011] External Links: Ensembl ID: ENSG00000126945 HGNC ID: HGNC:5042 Entrez Gene: 3188

Expression Profile of HNRNPH2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-155-5p YES YES NO hsa-miR-17-5p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-217 YES YES NO hsa-miR-300 YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-324-5p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-421 YES YES NO hsa-miR-429 YES YES NO hsa-miR-486-5p YES YES NO hsa-miR-487b-3p YES YES NO hsa-miR-495-3p YES YES YES hsa-miR-519d-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-7-5p YES YES NO hsa-miR-93-5p YES YES NO Display: