ctcRbase

Entry Detail

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General Information

Database ID: BRCA06972 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: MAP2K6 Full Name: mitogen-activated protein kinase kinase 6 Category: mRNA Synonyms: MAPKK6|MEK6|MKK6|PRKMK6|SAPKK-3|SAPKK3 Chromosome: chr17 Strand: + Coordinate: Start Site(bp): 69414698 End Site(bp): 69543331 Gene Summary: This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000108984 HGNC ID: HGNC:6846 Entrez Gene: 5608

Expression Profile of MAP2K6 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-5p YES YES NO hsa-miR-1298-5p YES NO YES hsa-miR-137 YES YES NO hsa-miR-140-3p YES NO YES hsa-miR-142-3p YES YES NO hsa-miR-153-3p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-29a-3p YES NO YES hsa-miR-29b-3p YES NO YES hsa-miR-29c-3p YES NO YES hsa-miR-340-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-378a-3p YES YES YES hsa-miR-422a YES YES YES hsa-miR-425-5p YES YES YES hsa-miR-448 YES YES YES Display: