ctcRbase

Entry Detail

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General Information

Database ID: BRCA07028 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: SNW1 Full Name: SNW domain containing 1 Category: mRNA Synonyms: Bx42|FUN20|NCOA-62|PRPF45|Prp45|SKIIP|SKIP|SKIP1 Chromosome: chr14 Strand: - Coordinate: Start Site(bp): 77717599 End Site(bp): 77761207 Gene Summary: This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] External Links: Ensembl ID: ENSG00000100603 HGNC ID: HGNC:16696 Entrez Gene: 22938

Expression Profile of SNW1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-1271-5p YES YES NO hsa-miR-142-3p YES YES NO hsa-miR-182-5p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-491-5p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-96-5p YES YES NO Display: