Entry Detail



General Information

Database ID:BRCA07040
Cancer Type:breast cancer
Dataset:GSE55807
CTCs/CTM Isolation Method:CTC-iChip



Gene Information

ncRNA Symbol:AES
Full Name:amino-terminal enhancer of split
Category:mRNA
Synonyms:AES-1|AES-2|ESP1|GRG|GRG5|Grg-5|TLE5
Chromosome:chr19
Strand:-
Coordinate:
Start Site(bp):3052910End Site(bp):3063107
Gene Summary:The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000104964
HGNC ID:HGNC:307
Entrez Gene:166



Expression Profile of AES Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-124-3p
YES
YES
YES
hsa-miR-506-3p
YES
YES
NO
hsa-miR-543
YES
YES
NO
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