ctcRbase

Entry Detail

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General Information

Database ID: BRCA07163 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: PMM2 Full Name: phosphomannomutase 2 Category: mRNA Synonyms: CDG1|CDG1a|CDGS|PMI|PMI1|PMM 2 Chromosome: chr16 Strand: + Coordinate: Start Site(bp): 8788823 End Site(bp): 8849331 Gene Summary: The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000140650 HGNC ID: HGNC:9115 Entrez Gene: 5373

Expression Profile of PMM2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES NO YES hsa-miR-125a-5p YES YES YES hsa-miR-125b-5p YES YES YES hsa-miR-144-3p YES YES YES hsa-miR-145-5p YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-25-3p YES YES NO hsa-miR-301a-3p YES YES NO hsa-miR-32-5p YES YES NO hsa-miR-363-3p YES YES NO hsa-miR-367-3p YES YES NO hsa-miR-384 YES YES NO hsa-miR-451a YES YES YES hsa-miR-491-5p YES YES NO hsa-miR-541-3p YES NO NO hsa-miR-582-5p YES NO YES hsa-miR-654-5p YES NO NO hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO Display: