ctcRbase

Entry Detail

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General Information

Database ID: BRCA07169 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: IDS Full Name: iduronate 2-sulfatase Category: mRNA Synonyms: MPS2|SIDS Chromosome: chrX Strand: - Coordinate: Start Site(bp): 149476990 End Site(bp): 149521096 Gene Summary: This gene encodes a member of the sulfatase family of proteins. The encoded preproprotein is proteolytically processed to generate two polypeptide chains. This enzyme is involved in the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this gene are associated with the X-linked lysosomal storage disease mucopolysaccharidosis type II, also known as Hunter syndrome. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016] External Links: Ensembl ID: ENSG00000010404 HGNC ID: HGNC:5389 Entrez Gene: 3423

Expression Profile of IDS Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES YES YES hsa-miR-128-3p YES YES NO hsa-miR-141-3p YES YES YES hsa-miR-154-5p YES YES NO hsa-miR-182-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-193a-3p YES YES NO hsa-miR-193b-3p YES YES NO hsa-miR-200a-3p YES YES YES hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-370-3p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-421 YES YES NO hsa-miR-429 YES YES YES hsa-miR-487b-3p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-499a-5p YES YES NO hsa-miR-7-5p YES YES YES hsa-miR-873-5p YES YES NO hsa-miR-889-3p YES NO NO hsa-miR-96-5p YES YES YES Display: