ctcRbase

Entry Detail

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General Information

Database ID: BRCA07386 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: PIM3 Full Name: Pim-3 proto-oncogene, serine/threonine kinase Category: mRNA Synonyms: pim-3 Chromosome: chr22 Strand: + Coordinate: Start Site(bp): 49960513 End Site(bp): 49964080 Gene Summary: The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is overexpressed in hematological and epithelial tumors and is associated with MYC coexpression. It plays a role in the regulation of signal transduction cascades, contributing to both cell proliferation and survival, and provides a selective advantage in tumorigenesis. [provided by RefSeq, Jun 2012] External Links: Ensembl ID: ENSG00000198355 HGNC ID: HGNC:19310 Entrez Gene: 415116

Expression Profile of PIM3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-1297 YES NO YES hsa-miR-15a-5p YES NO YES hsa-miR-15b-5p YES NO YES hsa-miR-16-5p YES NO YES hsa-miR-195-5p YES NO YES hsa-miR-26a-5p YES NO YES hsa-miR-26b-5p YES NO YES hsa-miR-329-3p YES YES NO hsa-miR-330-3p YES NO YES hsa-miR-33a-5p YES YES YES hsa-miR-33b-5p YES YES YES hsa-miR-362-3p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-424-5p YES NO YES hsa-miR-486-5p YES YES NO hsa-miR-497-5p YES NO YES hsa-miR-506-3p YES YES NO hsa-miR-875-5p YES YES NO hsa-miR-9-5p YES NO YES Display: