ctcRbase

Entry Detail

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General Information

Database ID: BRCA07387 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: ABHD12 Full Name: abhydrolase domain containing 12 Category: mRNA Synonyms: ABHD12A|BEM46L2|C20orf22|PHARC|dJ965G21.2 Chromosome: chr20 Strand: - Coordinate: Start Site(bp): 25294743 End Site(bp): 25390983 Gene Summary: This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jan 2011] External Links: Ensembl ID: ENSG00000100997 HGNC ID: HGNC:15868 Entrez Gene: 26090

Expression Profile of ABHD12 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-150-5p YES YES NO hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-370-3p YES YES NO hsa-miR-488-3p YES YES NO Display: