ctcRbase

Entry Detail

---



General Information

Database ID: BRCA07596 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: DPM2 Full Name: dolichyl-phosphate mannosyltransferase subunit 2, regulatory Category: mRNA Synonyms: CDG1U Chromosome: chr9 Strand: - Coordinate: Start Site(bp): 127935099 End Site(bp): 127938484 Gene Summary: Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a hydrophobic protein that contains 2 predicted transmembrane domains and a putative ER localization signal near the C terminus. This protein associates with DPM1 in vivo and is required for the ER localization and stable expression of DPM1 and also enhances the binding of dolichol-phosphate to DPM1. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000136908 HGNC ID: HGNC:3006 Entrez Gene: 8818

Expression Profile of DPM2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-125a-5p YES YES NO hsa-miR-125b-5p YES YES NO hsa-miR-22-3p YES YES YES hsa-miR-31-5p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-338-3p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-542-3p YES YES NO Display: