ctcRbase

Entry Detail

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General Information

Database ID: BRCA07742 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: GLRX3 Full Name: glutaredoxin 3 Category: mRNA Synonyms: GLRX4|GRX3|GRX4|PICOT|TXNL2|TXNL3 Chromosome: chr10 Strand: + Coordinate: Start Site(bp): 130136399 End Site(bp): 130184521 Gene Summary: This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010] External Links: Ensembl ID: ENSG00000108010 HGNC ID: HGNC:15987 Entrez Gene: 10539

Expression Profile of GLRX3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-5p YES YES NO hsa-miR-137 YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-25-3p YES YES NO hsa-miR-32-5p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-363-3p YES YES NO hsa-miR-367-3p YES YES NO hsa-miR-384 YES YES NO hsa-miR-873-5p YES YES NO hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO Display: