ctcRbase

Entry Detail

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General Information

Database ID: BRCA07827 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: MITF Full Name: melanocyte inducing transcription factor Category: mRNA Synonyms: CMM8|COMMAD|MI|WS2|WS2A|bHLHe32 Chromosome: chr3 Strand: + Coordinate: Start Site(bp): 69739435 End Site(bp): 69968337 Gene Summary: The protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. [provided by RefSeq, Aug 2017] External Links: Ensembl ID: ENSG00000187098 HGNC ID: HGNC:7105 Entrez Gene: 4286

Expression Profile of MITF Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-1271-5p YES YES NO hsa-miR-1298-5p YES NO YES hsa-miR-132-3p YES YES NO hsa-miR-137 YES YES YES hsa-miR-148a-3p YES YES YES hsa-miR-148b-3p YES YES YES hsa-miR-152-3p YES YES NO hsa-miR-153-3p YES YES YES hsa-miR-155-5p YES YES NO hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-182-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-199a-5p YES YES NO hsa-miR-199b-5p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-216a-5p YES YES YES hsa-miR-216b-5p YES NO YES hsa-miR-218-5p YES YES YES hsa-miR-221-3p YES YES YES hsa-miR-222-3p YES YES YES hsa-miR-224-5p YES YES NO hsa-miR-25-3p YES NO YES hsa-miR-300 YES YES NO hsa-miR-323a-3p YES NO YES hsa-miR-32-5p YES NO YES hsa-miR-363-3p YES NO YES hsa-miR-367-3p YES NO YES hsa-miR-375 YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-448 YES NO YES hsa-miR-506-3p YES YES NO hsa-miR-655-3p YES NO YES hsa-miR-876-5p YES YES NO hsa-miR-92a-3p YES NO YES hsa-miR-92b-3p YES NO YES hsa-miR-96-5p YES YES NO Display: