ctcRbase

Entry Detail

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General Information

Database ID: BRCA07829 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: UBE2L3 Full Name: ubiquitin conjugating enzyme E2 L3 Category: mRNA Synonyms: E2-F1|L-UBC|UBCH7|UbcM4 Chromosome: chr22 Strand: + Coordinate: Start Site(bp): 21549447 End Site(bp): 21624034 Gene Summary: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009] External Links: Ensembl ID: ENSG00000185651 HGNC ID: HGNC:12488 Entrez Gene: 7332

Expression Profile of UBE2L3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES YES hsa-miR-107 YES YES YES hsa-miR-122-5p YES YES NO hsa-miR-125a-5p YES NO YES hsa-miR-125b-5p YES NO YES hsa-miR-1271-5p YES NO YES hsa-miR-128-3p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-182-5p YES NO YES hsa-miR-223-3p YES YES NO hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-342-3p YES YES YES hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-370-3p YES NO YES hsa-miR-377-3p YES YES NO hsa-miR-409-5p YES NO YES hsa-miR-411-5p YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-451a YES YES NO hsa-miR-488-3p YES YES YES hsa-miR-494-3p YES YES NO hsa-miR-496 YES YES NO hsa-miR-542-3p YES YES NO hsa-miR-744-5p YES NO YES hsa-miR-96-5p YES NO YES Display: