ctcRbase

Entry Detail

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General Information

Database ID: BRCA07845 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: ADH5 Full Name: alcohol dehydrogenase 5 (class III), chi polypeptide Category: mRNA Synonyms: ADH-3|ADHX|FALDH|FDH|GSH-FDH|GSNOR|HEL-S-60p Chromosome: chr4 Strand: - Coordinate: Start Site(bp): 99070978 End Site(bp): 99088801 Gene Summary: This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene. [provided by RefSeq, Oct 2008] External Links: Ensembl ID: ENSG00000197894 HGNC ID: HGNC:253 Entrez Gene: 128

Expression Profile of ADH5 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-124-3p YES YES NO hsa-miR-128-3p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-139-5p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-182-5p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-206 YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-485-5p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-874-3p YES YES NO Display: