Entry Detail



General Information

Database ID:BRCA07877
Cancer Type:breast cancer
Dataset:GSE55807
CTCs/CTM Isolation Method:CTC-iChip



Gene Information

ncRNA Symbol:EXOSC1
Full Name:exosome component 1
Category:mRNA
Synonyms:CGI-108|CSL4|Csl4p|SKI4|Ski4p|p13
Chromosome:chr10
Strand:-
Coordinate:
Start Site(bp):97436142End Site(bp):97446017
Gene Summary:This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2016]
External Links:
Ensembl ID:ENSG00000171311
HGNC ID:HGNC:17286
Entrez Gene:51013



Expression Profile of EXOSC1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-103a-3p
YES
YES
NO
hsa-miR-107
YES
YES
NO
hsa-miR-15a-5p
YES
YES
NO
hsa-miR-15b-5p
YES
YES
NO
hsa-miR-16-5p
YES
YES
NO
hsa-miR-195-5p
YES
YES
NO
hsa-miR-424-5p
YES
YES
NO
hsa-miR-494-3p
YES
YES
NO
hsa-miR-497-5p
YES
YES
NO
hsa-miR-7-5p
YES
YES
NO
hsa-miR-873-5p
YES
YES
NO
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