ctcRbase

Entry Detail

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General Information

Database ID: BRCA07934 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: BRAT1 Full Name: BRCA1 associated ATM activator 1 Category: mRNA Synonyms: BAAT1|C7orf27|NEDCAS|RMFSL Chromosome: chr7 Strand: - Coordinate: Start Site(bp): 2537877 End Site(bp): 2555727 Gene Summary: The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM. [provided by RefSeq, Mar 2012] External Links: Ensembl ID: ENSG00000106009 HGNC ID: HGNC:21701 Entrez Gene: 221927

Expression Profile of BRAT1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-224-5p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-655-3p YES NO YES hsa-miR-876-5p YES YES NO Display: