ctcRbase

Entry Detail

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General Information

Database ID: BRCA08086 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: ORC4 Full Name: origin recognition complex subunit 4 Category: mRNA Synonyms: ORC4L|ORC4P Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 147930397 End Site(bp): 148021604 Gene Summary: The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene. [provided by RefSeq, Oct 2010] External Links: Ensembl ID: ENSG00000115947 HGNC ID: HGNC:8490 Entrez Gene: 5000

Expression Profile of ORC4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-132-3p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-190a-5p YES YES NO hsa-miR-190b YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-31-5p YES YES NO hsa-miR-340-5p YES NO YES hsa-miR-370-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-433-3p YES YES NO hsa-miR-9-5p YES YES NO Display: