| ncRNA Symbol: | NFU1 |
| Full Name: | NFU1 iron-sulfur cluster scaffold |
| Category: | mRNA |
| Synonyms: | CGI-33|HIRIP|HIRIP5|MMDS1|NIFUC|Nfu|NifU |
| Chromosome: | chr2 |
| Strand: | - |
| Coordinate: | | Start Site(bp): | 69395750 | End Site(bp): | 69437628 |
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| Gene Summary: | This gene encodes a protein that is localized to mitochondria and plays a critical role in iron-sulfur cluster biogenesis. The encoded protein assembles and transfers 4Fe-4S clusters to target apoproteins including succinate dehydrogenase and lipoic acid synthase. Mutations in this gene are a cause of multiple mitochondrial dysfunctions syndrome-1, and pseudogenes of this gene are located on the short arms of chromosomes 1 and 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
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