ctcRbase

Entry Detail

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General Information

Database ID: BRCA08356 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: ZFR Full Name: zinc finger RNA binding protein Category: mRNA Synonyms: SPG71|ZFR1 Chromosome: chr5 Strand: - Coordinate: Start Site(bp): 32354350 End Site(bp): 32444761 Gene Summary: This gene encodes an RNA-binding protein characterized by its DZF (domain associated with zinc fingers) domain. The encoded protein may play a role in the nucleocytoplasmic shuttling of another RNA-binding protein, Staufen homolog 2, in neurons. Expression of this gene is regulated through alternative polyadenylation that mediates differential microRNA targeting. Elevated expression of this gene has been observed in human patients with pancreatic cancer and knockdown of this gene may result in reduced viability and invasion of pancreatic cancer cells. [provided by RefSeq, Sep 2016] External Links: Ensembl ID: ENSG00000056097 HGNC ID: HGNC:17277 Entrez Gene: 51663

Expression Profile of ZFR Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-5p YES YES NO hsa-miR-141-3p YES YES YES hsa-miR-142-3p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-200a-3p YES YES YES hsa-miR-205-5p YES YES NO hsa-miR-208a-3p YES YES NO hsa-miR-208b-3p YES YES NO hsa-miR-216a-5p YES YES YES hsa-miR-216b-5p YES NO YES hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-342-3p YES YES YES hsa-miR-361-5p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-421 YES YES NO hsa-miR-485-5p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-499a-5p YES YES NO hsa-miR-505-3p YES YES NO hsa-miR-520f-3p YES NO YES hsa-miR-543 YES YES NO hsa-miR-875-5p YES YES NO Display: