ctcRbase

Entry Detail

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General Information

Database ID: BRCA08426 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: HNRNPAB Full Name: heterogeneous nuclear ribonucleoprotein A/B Category: mRNA Synonyms: ABBP1|HNRPAB Chromosome: chr5 Strand: + Coordinate: Start Site(bp): 178204507 End Site(bp): 178211163 Gene Summary: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000197451 HGNC ID: HGNC:5034 Entrez Gene: 3182

Expression Profile of HNRNPAB Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES NO YES hsa-miR-1197 YES NO YES hsa-miR-141-3p YES YES YES hsa-miR-144-3p YES YES YES hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-200a-3p YES YES YES hsa-miR-340-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-421 YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-505-3p YES YES NO hsa-miR-542-3p YES YES NO hsa-miR-599 YES YES NO hsa-miR-625-5p YES NO NO hsa-miR-873-5p YES YES NO hsa-miR-875-5p YES YES NO Display: