ctcRbase

Entry Detail

---



General Information

Database ID: BRCA08489 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: DLD Full Name: dihydrolipoamide dehydrogenase Category: mRNA Synonyms: DLDD|DLDH|E3|GCSL|LAD|PHE3 Chromosome: chr7 Strand: + Coordinate: Start Site(bp): 107890970 End Site(bp): 107931730 Gene Summary: This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] External Links: Ensembl ID: ENSG00000091140 HGNC ID: HGNC:2898 Entrez Gene: 1738

Expression Profile of DLD Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-125a-5p YES YES NO hsa-miR-125b-5p YES YES NO hsa-miR-1271-5p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-1-3p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-190a-5p YES YES NO hsa-miR-190b YES YES NO hsa-miR-206 YES YES NO hsa-miR-208a-3p YES YES NO hsa-miR-208b-3p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-23a-3p YES NO YES hsa-miR-23b-3p YES NO YES hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-365a-3p YES YES NO hsa-miR-370-3p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-433-3p YES YES NO hsa-miR-455-3p YES NO YES hsa-miR-494-3p YES NO YES hsa-miR-496 YES YES NO hsa-miR-499a-5p YES YES YES hsa-miR-613 YES YES NO hsa-miR-655-3p YES NO YES hsa-miR-876-5p YES YES NO hsa-miR-96-5p YES YES NO Display: