ctcRbase

Entry Detail

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General Information

Database ID: BRCA08657 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: DNM1L Full Name: dynamin 1 like Category: mRNA Synonyms: DLP1|DRP1|DVLP|DYMPLE|EMPF|EMPF1|HDYNIV|OPA5 Chromosome: chr12 Strand: + Coordinate: Start Site(bp): 32679200 End Site(bp): 32745650 Gene Summary: This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013] External Links: Ensembl ID: ENSG00000087470 HGNC ID: HGNC:2973 Entrez Gene: 10059

Expression Profile of DNM1L Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-130a-3p YES YES NO hsa-miR-130b-3p YES YES NO hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-301a-3p YES YES NO hsa-miR-301b-3p YES YES NO hsa-miR-454-3p YES YES NO hsa-miR-499a-5p YES YES YES hsa-miR-505-3p YES YES YES hsa-miR-590-5p YES YES NO hsa-miR-802 YES NO YES Display: