Entry Detail



General Information

Database ID:BRCA09361
Cancer Type:breast cancer
Dataset:GSE111065
CTCs/CTM Isolation Method:microfluidics immunofluorescence



Gene Information

ncRNA Symbol:EFNA4
Full Name:ephrin A4
Category:mRNA
Synonyms:EFL4|EPLG4|LERK4
Chromosome:chr1
Strand:+
Coordinate:
Start Site(bp):155063731End Site(bp):155069553
Gene Summary:This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin. Three transcript variants that encode distinct proteins have been identified. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000243364
HGNC ID:HGNC:3224
Entrez Gene:1945



Expression Profile of EFNA4 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-133a-3p
YES
YES
YES
hsa-miR-133b
YES
YES
YES
hsa-miR-140-5p
YES
YES
NO
hsa-miR-299-5p
YES
NO
YES
hsa-miR-340-5p
NO
YES
YES
hsa-miR-376a-3p
YES
YES
NO
hsa-miR-376b-3p
YES
YES
NO
hsa-miR-431-5p
YES
YES
NO
hsa-miR-874-3p
YES
YES
NO
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