| ncRNA Symbol: | IBA57 |
| Full Name: | IBA57, iron-sulfur cluster assembly |
| Category: | mRNA |
| Synonyms: | C1orf69|MMDS3|SPG74 |
| Chromosome: | chr1 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 228165815 | End Site(bp): | 228182257 | |
| Gene Summary: | The protein encoded by this gene localizes to the mitochondrion and is part of the iron-sulfur cluster assembly pathway. The encoded protein functions late in the biosynthesis of mitochondrial 4Fe-4S proteins. Defects in this gene have been associated with autosomal recessive spastic paraplegia-74 and with multiple mitochondrial dysfunctions syndrome-3. Two transcript variants encoding different isoforms have been found for this gene. The smaller isoform is not likely to be localized to the mitochondrion since it lacks the amino-terminal transit peptide. [provided by RefSeq, Jul 2015] |
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