Entry Detail



General Information

Database ID:BRCA09672
Cancer Type:breast cancer
Dataset:GSE41245
CTCs/CTM Isolation Method:CTC-Chip



Gene Information

ncRNA Symbol:IBA57
Full Name:IBA57, iron-sulfur cluster assembly
Category:mRNA
Synonyms:C1orf69|MMDS3|SPG74
Chromosome:chr1
Strand:+
Coordinate:
Start Site(bp):228165815End Site(bp):228182257
Gene Summary:The protein encoded by this gene localizes to the mitochondrion and is part of the iron-sulfur cluster assembly pathway. The encoded protein functions late in the biosynthesis of mitochondrial 4Fe-4S proteins. Defects in this gene have been associated with autosomal recessive spastic paraplegia-74 and with multiple mitochondrial dysfunctions syndrome-3. Two transcript variants encoding different isoforms have been found for this gene. The smaller isoform is not likely to be localized to the mitochondrion since it lacks the amino-terminal transit peptide. [provided by RefSeq, Jul 2015]
External Links:
Ensembl ID:ENSG00000181873
HGNC ID:HGNC:27302
Entrez Gene:200205



Expression Profile of IBA57 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-122-5p
YES
NO
NO
hsa-miR-205-5p
YES
YES
NO
hsa-miR-329-3p
YES
NO
NO
hsa-miR-362-3p
YES
NO
NO
hsa-miR-496
YES
YES
NO
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