ctcRbase

Entry Detail

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General Information

Database ID: BRCA09719 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: MYO6 Full Name: myosin VI Category: mRNA Synonyms: DFNA22|DFNB37|Myo6-007|Myo6-008 Chromosome: chr6 Strand: + Coordinate: Start Site(bp): 75749192 End Site(bp): 75919537 Gene Summary: This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014] External Links: Ensembl ID: ENSG00000196586 HGNC ID: HGNC:7605 Entrez Gene: 4646

Expression Profile of MYO6 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-140-5p YES YES NO hsa-miR-143-3p YES YES YES hsa-miR-145-5p YES NO YES hsa-miR-186-5p YES YES NO hsa-miR-196a-5p YES YES NO hsa-miR-196b-5p YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-384 YES YES YES hsa-miR-455-3p YES NO YES hsa-miR-590-5p YES YES NO hsa-miR-625-5p YES NO NO hsa-miR-876-5p YES YES NO Display: