ctcRbase

Entry Detail

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General Information

Database ID: BRCA10035 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: SMARCB1 Full Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Category: mRNA Synonyms: BAF47|CSS3|INI1|MRD15|PPP1R144|RDT|RTPS1|SNF5|SNF5L1|SWNTS1|Sfh1p|Snr1|hSNFS Chromosome: chr22 Strand: + Coordinate: Start Site(bp): 23786963 End Site(bp): 23834516 Gene Summary: The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015] External Links: Ensembl ID: ENSG00000099956 HGNC ID: HGNC:11103 Entrez Gene: 6598

Expression Profile of SMARCB1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1-3p YES YES YES hsa-miR-192-5p YES YES NO hsa-miR-206 YES YES YES hsa-miR-215-5p YES YES NO hsa-miR-541-3p YES NO NO hsa-miR-613 YES YES YES hsa-miR-654-5p YES NO NO Display: