ctcRbase

Entry Detail

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General Information

Database ID: BRCA10230 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: GAA Full Name: glucosidase alpha, acid Category: mRNA Synonyms: LYAG Chromosome: chr17 Strand: + Coordinate: Start Site(bp): 80101556 End Site(bp): 80119879 Gene Summary: This gene encodes lysosomal alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. The encoded preproprotein is proteolytically processed to generate multiple intermediate forms and the mature form of the enzyme. Defects in this gene are the cause of glycogen storage disease II, also known as Pompe's disease, which is an autosomal recessive disorder with a broad clinical spectrum. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] External Links: Ensembl ID: ENSG00000171298 HGNC ID: HGNC:4065 Entrez Gene: 2548

Expression Profile of GAA Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-150-5p YES YES NO hsa-miR-25-3p YES YES YES hsa-miR-28-5p YES YES NO hsa-miR-32-5p YES YES YES hsa-miR-363-3p YES YES YES hsa-miR-365a-3p YES YES NO hsa-miR-367-3p YES YES YES hsa-miR-708-5p YES YES NO hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES Display: