ctcRbase

Entry Detail

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General Information

Database ID: BRCA10797 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: PDE4A Full Name: phosphodiesterase 4A Category: mRNA Synonyms: DPDE2|PDE4|PDE46 Chromosome: chr19 Strand: + Coordinate: Start Site(bp): 10416773 End Site(bp): 10469631 Gene Summary: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011] External Links: Ensembl ID: ENSG00000065989 HGNC ID: HGNC:8780 Entrez Gene: 5141

Expression Profile of PDE4A Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-10a-5p YES YES YES hsa-miR-10b-5p YES YES YES hsa-miR-124-3p YES NO YES hsa-miR-129-5p YES YES YES hsa-miR-135a-5p YES NO YES hsa-miR-135b-5p YES NO YES hsa-miR-137 YES NO YES hsa-miR-139-5p YES NO YES hsa-miR-144-3p YES YES YES hsa-miR-186-5p YES NO NO hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-204-5p YES YES YES hsa-miR-211-5p YES YES YES hsa-miR-214-3p YES YES NO hsa-miR-28-5p YES YES NO hsa-miR-346 YES YES NO hsa-miR-369-3p YES NO YES hsa-miR-374a-5p YES NO YES hsa-miR-374b-5p YES NO YES hsa-miR-375 YES YES NO hsa-miR-431-5p YES YES NO hsa-miR-486-5p YES YES YES hsa-miR-582-5p YES NO YES hsa-miR-655-3p YES NO YES hsa-miR-7-5p YES YES YES hsa-miR-873-5p YES YES NO Display: