ctcRbase

Entry Detail

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General Information

Database ID: BRCA11414 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: NR3C2 Full Name: nuclear receptor subfamily 3 group C member 2 Category: mRNA Synonyms: MCR|MLR|MR|NR3C2VIT Chromosome: chr4 Strand: - Coordinate: Start Site(bp): 148078762 End Site(bp): 148444698 Gene Summary: This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] External Links: Ensembl ID: ENSG00000151623 HGNC ID: HGNC:7979 Entrez Gene: 4306

Expression Profile of NR3C2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-5p YES YES NO hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-135a-5p YES YES YES hsa-miR-135b-5p YES YES YES hsa-miR-155-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-205-5p YES YES NO hsa-miR-217 YES YES NO hsa-miR-25-3p YES YES NO hsa-miR-28-3p YES NO YES hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-30a-5p YES NO YES hsa-miR-30b-5p YES NO YES hsa-miR-30c-5p YES NO YES hsa-miR-30d-5p YES NO YES hsa-miR-30e-5p YES NO YES hsa-miR-32-5p YES YES NO hsa-miR-338-3p YES YES YES hsa-miR-363-3p YES YES NO hsa-miR-365a-3p YES YES YES hsa-miR-367-3p YES YES NO hsa-miR-454-3p YES YES YES hsa-miR-455-5p YES NO YES hsa-miR-495-3p YES YES NO hsa-miR-599 YES YES NO hsa-miR-873-5p YES YES NO hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO Display: