ctcRbase

Entry Detail

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General Information

Database ID: BRCA11520 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: PER1 Full Name: period circadian regulator 1 Category: mRNA Synonyms: PER|RIGUI|hPER Chromosome: chr17 Strand: - Coordinate: Start Site(bp): 8140472 End Site(bp): 8156506 Gene Summary: This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers. Alternative splicing has been observed in this gene; however, these variants have not been fully described. [provided by RefSeq, Jan 2014] External Links: Ensembl ID: ENSG00000179094 HGNC ID: HGNC:8845 Entrez Gene: 5187

Expression Profile of PER1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-5p YES YES NO hsa-miR-138-5p YES YES YES hsa-miR-146a-5p YES NO YES hsa-miR-146b-5p YES NO YES hsa-miR-194-5p YES YES NO hsa-miR-24-3p YES YES YES hsa-miR-29a-3p YES NO YES hsa-miR-29b-3p YES NO YES hsa-miR-29c-3p YES NO YES hsa-miR-423-5p YES NO YES Display: