ctcRbase

Entry Detail

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General Information

Database ID: BRCA11529 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: WWP2 Full Name: WW domain containing E3 ubiquitin protein ligase 2 Category: mRNA Synonyms: AIP2|WWp2-like Chromosome: chr16 Strand: + Coordinate: Start Site(bp): 69762306 End Site(bp): 69941741 Gene Summary: This gene encodes a member of the Nedd4 family of E3 ligases, which play an important role in protein ubiquitination. The encoded protein contains four WW domains and may play a role in multiple processes including chondrogenesis and the regulation of oncogenic signaling pathways via interactions with Smad proteins and the tumor suppressor PTEN. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 10. [provided by RefSeq, Jul 2012] External Links: Ensembl ID: ENSG00000198373 HGNC ID: HGNC:16804 Entrez Gene: 11060

Expression Profile of WWP2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1297 YES NO YES hsa-miR-137 YES NO YES hsa-miR-147a YES NO NO hsa-miR-154-5p YES YES NO hsa-miR-205-5p YES YES NO hsa-miR-219a-5p YES NO YES hsa-miR-22-3p YES YES NO hsa-miR-25-3p YES YES YES hsa-miR-26a-5p YES NO YES hsa-miR-26b-5p YES NO YES hsa-miR-32-5p YES YES YES hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-376c-3p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-503-5p YES YES NO hsa-miR-542-3p YES YES NO hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES hsa-miR-9-5p YES YES NO Display: